Elmiron (Pentosan Polysulfate Sodium)

Elmiron is a chemical which is approved by the Food and Drug Administration for the treatment of interstitial cystitis.

How is the drug taken?
The drug is taken by mouth three times a day. The capsules should be taken with water at least one hour before meals or two hours after meals.

How long does it take for the medication to work?
Most patients will receive relief by three months after taking the medication. If no improvement has occurred by three months and there have been no serious side effects from the use of Elmiron, a second three-month trial could be tried.

What are the side effects from this medication?
Nausea, headache, diarrhea, rash, abdominal pain, dizziness, and loss of hair (which is reversible) occur in one to four percent of the patients who use the drug. A very mild form of hepatitis may occur in less than two percent of patients.

What other precautions should I take with this drug?
Elmiron is a weak anticoagulant (blood thinner) and may prolong the prothrombin time and partial thromboplastin time. If you are taking blood thinners or bruise easily, please notify us before taking this medication.