Negram or Nalidixic Acid

Why is this drug prescribed?
Nalidixic acid eliminates bacteria that cause urinary tract infections.

When should it be used?
Nalidixic acid is usually taken four times a day for seven to 14 days. Follow the instructions on your prescription label, and ask your pharmacist to explain any part that you do not understand. To be effective, doses should be taken at evenly spaced intervals. For example, if you are to take this drug four times a day, take a dose every six hours. If you cannot take the medication around the clock, however, take it at evenly spaced intervals between the time you wake up and the time you go to bed.

How should it be used?
Nalidixic acid comes in tablets and oral liquid. Take it with a full glass of water on an empty stomach, at least one hour before or two hours after meals. Shake the liquid well before each use to mix the medication evenly. You may obtain a specially marked measuring spoon from your pharmacist to be sure of an accurate dose. Since nalidixic acid usually is prescribed for a limited time, your prescription probably will not have refills. If you have taken all this drug and still have symptoms, contact us.

What special instructions should I follow while using this drug?
Drink at least eight full glasses of water or other liquids every day. Take all of the nalidixic acid prescribed, even if you begin to feel better. Symptoms of the infection may disappear before the infection is cured. If you will be outside for long periods, wear clothing that protects your skin from direct sunlight. Use sunscreen agents for uncovered skin areas. You may have urine tests done to determine when the infection is cured. Keep all appointments with us and the laboratory. Nalidixic acid can cause drowsiness and dizziness. Do not drive a car or operate dangerous machinery until you know how this drug affects you.

What should I do if I forget to take a dose?
Take the missed dose as soon as you remember it. Take any remaining doses for that day at evenly spaced intervals. It is important to take all doses of this medication on time, especially during the first few days of treatment. If you fail to take the doses as scheduled, bacteria can build up defenses (resistance) against the effects of nalidixic acid.

What side effects can this drug cause? What can I do about them?
To combat nausea, vomiting, abdominal pain, or diarrhea, take this drug with meals or a snack. If you still experience these effects, contact us. If you experience muscle pain, confusion, depression, weakness, headache, dizziness, faintness, or unusual sensations, contact us if the effects are severe or persist. If you experience skin rash, or seizures (which rarely occur), stop taking the medication and contact us.

What other precautions should I follow while using this drug?
Diabetics should use Clinistix or TesTape instead of Clinitest to test their urine for sugar. Nalidixic acid can cause Clinitest to show false results. Before taking nalidixic acid, tell us if you are less than three months pregnant, think that you may be pregnant, or have epilepsy or liver, lung, or kidney disease. Tell us if you take anticoagulants ("blood thinners"), such as Warfarin. If you are told to stop taking nalidixic acid, throw away any unused medication. Nalidixic acid loses effectiveness over time and should not be saved to treat another infection. Do not allow anyone else to take this medication.
Nilandron, alone or in combination with Lupron or Zolodex, may cause a reduction in sex drive and impotence (difficulty achieving or maintaining an erection). Your personality and masculine identity will NOT be changed. The only way to treat sexual problems is to give you male hormones, which would defeat the purpose of the medications and make the cancer grow.