BCG Instillation


The medication will be instilled into your bladder through a catheter. In most cases, the catheter will be removed from the bladder immediately after the instillation has been completed. The medication should be retained in your bladder for about two hours to obtain the best results. If you MUST urinate before two hours, the medicine will still be effective, but let us know at your next visit how long you held the BCG. You should remain active after the instillation to move the medicine around in the bladder. If you want to lie down, you should plan to move positions from side-to-side and back-to-front every 15 minutes while the medication is in your bladder.


After retaining the medication in your bladder for two hours, it must be carefully disposed of in the following manner:

Sit down on the toilet to urinate and fully empty your bladder. After urinating, pour two (2) cups of household bleach (Clorox or equivalent) into the toilet. Let the medication and Clorox mixture stay in the toilet for 15-20 minutes before flushing. Repeat the above process each time you urinate for six (6) hours after each treatment. Wash your hands and genital areas thoroughly after you urinate. Drink plenty of fluids after the instillation to flush your bladder.


You may experience some burning and frequency of urination with the first few voidings after your treatment. If this occurs, increase your fluid intake. Call us if you experience:

  • Continuous pain or burning on urination.
  • Bright red blood or blood clots in the urine.
  • Severe urgency of urination with incontinence (involuntary loss of urine).
  • Severe frequency of urination.
  • Fever, chills or malaise (generalized feeling of discomfort or illness).
  • Joint pain.
  • Prolonged coughing.

If you have any questions about your BCG treatment, call us.